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chemokine (C-C motif) ligand 25 | |||||||
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Identifiers | |||||||
Symbol | CCL25 | ||||||
Alt. symbols | SCYA25, TECK, Ckb15 | ||||||
NCBI gene | 6370 | ||||||
HGNC | 10624 | ||||||
OMIM | 602565 | ||||||
RefSeq | NM_005624 | ||||||
UniProt | O15444 | ||||||
Other data | |||||||
Locus | Chr. 19 p13.2 | ||||||
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Chemokine (C-C motif) ligand 25 (CCL25) is a small cytokine belonging to the CC chemokine family that is also known as TECK (Thymus-Expressed Chemokine). CCL25 is believed to play a role in the development of T-cells.[1] It is chemotactic for thymocytes, macrophages, and dendritic cells. CCL25 elicits its effects by binding to the chemokine receptor CCR9.[2][3] Human CCL25 is produced as a protein precursor containing 151 amino acids. The gene for CCL25 (scya25) is located on human chromosome 19.[4]