| EAL domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 crystal structure of the bacillus subtilis ykui protein, with an eal domain. | |||||||||
| Identifiers | |||||||||
| Symbol | EAL | ||||||||
| Pfam | PF00563 | ||||||||
| InterPro | IPR001633 | ||||||||
| CDD | cd01948 | ||||||||
| |||||||||
In molecular biology, the EAL domain is a conserved protein domain. It is found in diverse bacterial signalling proteins. It is named EAL after its conserved residues. The EAL domain may function as a diguanylate phosphodiesterase.[1] The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
References
[edit]- ^ Galperin MY, Nikolskaya AN, Koonin EV (September 2001). "Novel domains of the prokaryotic two-component signal transduction systems". FEMS Microbiol. Lett. 203 (1): 11–21. doi:10.1016/S0378-1097(01)00326-3. PMID 11557134.