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Herman I. Quackenboss (January 8, 1792 Washington County, New York - November 19, 1874 Lansingburgh, Rensselaer County, New York) was an American politician from New York.
He was the son of John H. Quackenboss (1766–1853) and Catrina (Van Woert) Quackenboss (b. 1768). He married Elizabeth, and they had three children. Herman I. Quackenboss was a tanner.
He was a member of the New York State Assembly, from Delaware Co. in 1825; from Greene Co. in 1828; and from New York Co. in 1835.
He was a member of the New York State Senate (3rd D.) from 1831 to 1834, sitting in the 54th, 55th, 56th and 57th New York State Legislatures.