Class of enzymes
Indolin-2-one monooxygenase (EC 1.14.13.138 , BX3 (gene) , CYP71C2 (gene) ) is an enzyme with systematic name indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating) .[ 1] [ 2] This enzyme catalyses the following chemical reaction
indolin-2-one + NAD(P)H + H+ + O2
⇌
{\displaystyle \rightleftharpoons }
3-hydroxyindolin-2-one + NAD(P)+ + H2 O
Indolin-2-one monooxygenase is involved in the biosynthesis of protective and allelopathic benzoxazinoids in some plants.
^ Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A (August 1997). "Analysis of a chemical plant defense mechanism in grasses". Science . 277 (5326): 696–9. doi :10.1126/science.277.5326.696 . PMID 9235894 .
^ Glawischnig E, Grün S, Frey M, Gierl A (March 1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses". Phytochemistry . 50 (6): 925–30. Bibcode :1999PChem..50..925G . doi :10.1016/s0031-9422(98)00318-5 . PMID 10385992 .
CYP1 CYP2 CYP3 (CYP3A ) CYP4 CYP5-20 CYP21-49 CYP51-69 CYP71-99
CYP71 (C1 , C2 , C3 , C4 , Z6 , AJ4 , AV1 , BA1 )
CYP72A1
CYP73A1
CYP74 (D1 )
CYP75 (A1 , B1 )
CYP76 (B6 , M7 )
CYP79 (A1 , A2 , B1 , B2 , B3 , D1 , D2 , D3 , D4 )
CYP80 (A1 , B1 , G2 )
CYP81 (E1 , E3 , E7 , E9 )
CYP88D6
CYP90C1
CYP93E1
CYP97C1
CYP99A3
CYP101-281 CYP301-499 CYP501-699 CYP701-999