After an experience with the quality productive Juventus youth system, Del Prete was loaned out to Pizzighettone and Lanciano to gain experience through first team playing time in the lower divisions of the Italian league.
After some impressive[according to whom?] performances Juventus opted to sell him in a co-ownership deal on 8 July 2008[2] to Serie A side Siena for €130,000,[nb 1] so he could gain experience at the highest level. He made his Serie A debut on the first day of the 2008–09 season in a defeat to Atalanta. His debut also activated the bonus clause regulated by FIGC, which Siena had to pay €18,000 per year to Monterotondo as Premio alla carriera.[nb 2] In June 2009 Siena bought him outright for another €130,000.[nb 3][6][7] Del Prete was signed by Frosinone in July 2009 along with Caetano Calil.[8] On 15 July 2010 he was signed by Pescara.[9][10] Circa 2010[11] Del Prete also renewed his contract to 30 June 2014.[2][12]
In 2011 Del Prete returned to Siena for their pre-season camp. He also received no.32 shirt[13] before he left the club again on 30 August 2011.[14]Nocerina also received €10,000 performance bonus (Italian: premi di valorizzazione) from Siena for the loan.[2]
On 20 July 2012, Del Prete was sold to Novara for €600,000 in a 4-year contract.[15] On the same time Siena signed Massimo Paci also for €600,000.[2][16] On 22 January 2013 Del Prete was signed by Crotone in temporary deal.[17] On 11 July 2013 the deal was renewed.[18]
On 1 April 2022, Del Prete returned to Novara in Serie D until the end of the season.[24] After making a 5-minute substitute appearance two days later, he was not included in the matchday squad for the rest of the season.
^Based on 50% of the contract residual value on 30 June 2008, €11,000,[1] and the profit that Juventus disclosed in 2008–09 financial report, €119,000[3]
^Siena disclosed that the club had paid €180,000[4] in total to the former clubs of Del Prete, Belmonte and Zito. However the breakdown of the payment which worth 10 season of services was unknown; Regulated by Article 99bis of N.O.I.F., Once the players had made his Serie A debut or U21 debut, the professional clubs had to pay the Premio alla carriera to youth and amateur club that the players had registered as "youth" giovane or "young amateur" (giovane dilettante).
^Based on 50% of the contract residual value on 30 June 2008, €11,000,[1] and the profit that Juventus disclosed in 2009–10 financial report, €119,000[5]